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Proteintech
BBS4 Recombinant Rabbit Monoclonal Antibody (230303C2)
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产品信息
82961-1-RR
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
230303C2
抗原
BBS4 fusion protein Ag3430
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice
产品详细信息
Immunogen sequence: MAEERVATRT QFPVSTESQK PRQKKAPEFP ILEKQNWLIH LHYIRKDYEA CKAVIKEQLQ ETQGLCEYAI YVQALIFRLE GNIQESLELF QTCAVLSPQS ADNLKQVARS LFLLGKHKAA IEVYNEAAKL NQKDWEISHN LGVCYIYLKQ FNKAQDQLHN ALNLNRHDLT YIMLGKIHLL EGDLDKAIEV YKKAVEFSPE NTELLTTLGL LYLQLGIYQK AFEHLGNALT YDPTNYKAIL AAGSMMQTHG DFDVALTKYR VVACAVPESP PLWNNIGMCF FGKKKYVAAI SCLKRANYLA PFDWKILYNL GLVHLTMQQY ASAFHFLSAA INFQPKMGEL YMLLAVALTN L
靶标信息
BBS4 contains tetratricopeptide repeats (TPR), similar to O-linked N-acetyglucosamine transferase. Mutations in the gene encoding this protein have been observed in patients with Bardet-Biedl syndrome type 4. BBS4 may play a role in pigmentary retinopathy, obesity, polydactyly, renal malformation and mental retardation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Bardet-Biedl syndrome 4 protein; BBSome complex member BBS4
基因别名: BBS4
UniProt ID: (Human) Q96RK4
Entrez Gene ID: (Human) 585
microtubule cytoskeleton organization
mitotic cytokinesis
neuron migration
neural tube closure
retina homeostasis
heart looping
negative regulation of systemic arterial blood pressure
spermatid development
visual perception
sensory perception of smell
negative regulation of gene expression
protein transport
dendrite development
regulation of lipid metabolic process
ventricular system development
striatum development
hippocampus development
cerebral cortex development
adult behavior
negative regulation of actin filament polymerization
melanosome transport
regulation of cytokinesis
protein localization to organelle
negative regulation of GTPase activity
microtubule anchoring at centrosome
nonmotile primary cilium assembly
social behavior
photoreceptor cell outer segment organization
negative regulation of appetite by leptin-mediated signaling pathway
positive regulation of multicellular organism growth
cilium assembly
fat cell differentiation
photoreceptor cell maintenance
positive regulation of cilium assembly
retinal rod cell development
intracellular transport
brain morphogenesis
sensory processing
centrosome organization
maintenance of protein location in nucleus
regulation of stress fiber assembly
cilium morphogenesis
regulation of cilium beat frequency involved in ciliary motility
face development
fat pad development
protein localization to cilium
protein localization to centrosome
regulation of nonmotile primary cilium assembly
protein localization to photoreceptor outer segment
