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Invitrogen
BEX1/BEX2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-100404
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human BEX2(Accession Q9BXY8), corresponding to amino acid residues M1-R50.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total BEX1/2.
靶标信息
BEX1/BEX2 belongs to the brain expressed X-linked gene family. The encoded protein interacts with the transcription factor LIM domain only 2 in a DNA-binding complex that recognizes the E-box element and promotes transcription. BEX1/BEX2 has been found to be a tumor suppressor that is silenced in human glioma. In breast cancer cells, this gene product modulates apoptosis in response to estrogen and tamoxifen, and enhances the anti-proliferative effect of tamoxifen. Multiple transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: brain expressed gene 1; brain expressed X-linked 1; brain expressed X-linked 2; brain-expressed X-linked protein 1; brain-expressed X-linked protein 1 homolog; brain-expressed X-linked protein 2; brain-expressed X-linked protein 2 homolog; EG2RVC; expression gene 2 in rat visual cortex; HGR74-h protein; ovarian granulosa cell 13.0 kDa protein hGR74; protein BEX1; protein BEX2; protein hBex2; reduced expression 3; reduced expression protein 3; retinoic acid reduced gene expression; REX-3; unnamed protein product
基因别名: Bex; BEX1; Bex1h; BEX2; Bex22; Bex4; DJ79P11.1; EG2RVC; HBEX2; HGR74-h; REX-3; Rex3
UniProt ID: (Human) Q9HBH7, (Human) Q9BXY8, (Rat) Q3MKQ2, (Mouse) Q9R224, (Rat) Q3MKQ1, (Mouse) Q9WTZ8
Entrez Gene ID: (Human) 55859, (Human) 84707, (Rat) 501625, (Mouse) 19716, (Rat) 363498, (Mouse) 12069
signal transduction
negative regulation of protein ubiquitination
positive regulation of transcription from RNA polymerase II promoter
regulation of apoptotic process
regulation of cell cycle
positive regulation of neuroblast proliferation
axon regeneration
negative regulation of neuron differentiation
axon development
neurotrophin TRK receptor signaling pathway
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