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Invitrogen
BFSP2 Polyclonal Antibody
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BFSP2 Antibody (PA5-88949) in WB
Western blot analysis of BFSP2 in extracts of mouse eye. Samples were incubated with BFSP2 Polyclonal antibody (Product # PA5-88949) using a dilution of 1:3,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.
产品信息
PA5-88949
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 116-415 of human BFSP2 (NP_0035621)
偶联物
形式
Liquid
浓度
2.11 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: VEYMAKVHAL EQVSQELETQ LRMHLESKAT RSGNWGALRA SWASSCQQVG EAVLENARLM LQTETIQAGA DDFKERYENE QPFRKAAEEE INSLYKVIDE ANLTKMDLES QIESLKEELG SLSRNYEEDV KLLHKQLAGC ELEQMDAPIG TGLDDILETI RIQWERDVEK NRVEAGALLQ AKQQAEVAHM SQTQEEKLAA ALRVELHNTS CQVQSLQAET ESLRALKRGL ENTLHDAKHW HDMELQNLGA VVGRLEAELR EIRAEAEQQQ QERAHLLARK CQLQKDVASY HALLDREESG; Positive Samples: Mouse eye; Cellular Location: Cell membrane, Cytoplasm, Cytoplasmic side, Peripheral membrane protein, cell cortex, cytoskeleton
靶标信息
More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, the protein product of this gene (phakinin), and filensin, are expressed only after fiber cell differentiation has begun. Both proteins are found in a structurally unique cytoskeletal element that is referred to as the beaded filament (BF). Mutations in this gene have been associated with juvenile-onset, progressive cataracts and Dowling-Meara epidermolysis bullosa simplex.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 49 kDa cytoskeletal protein; Beaded filament structural protein 2; CP47; CP49; Lens fiber cell beaded filament protein CP 47; Lens fiber cell beaded filament protein CP 49; Lens intermediate filament-like light; LIFL-L; MGC142078; MGC142080; Phakinin
基因别名: AI448593; Bfsp2; CP49
UniProt ID: (Mouse) Q6NVD9
Entrez Gene ID: (Mouse) 107993
