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Invitrogen
BHLHB5 Polyclonal Antibody
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BHLHB5 Antibody (PA5-64326) in ICC/IF
Immunofluorescence analysis of BHLHB5 was performed using log phase THP-1 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 1 hour at room temperature. The cells were labeled with BHLHB5 Polyclonal Antibody (Product # PA5-64326) at 1:100 dilution in 0.1% BSA, incubated at 4 degree Celsius overnight and then labeled with Goat anti-Rabbit IgG (Heavy Chain) Superclonal™ Secondary Antibody, Alexa Fluor® 488 conjugate (Product # A27034) at a dil... View More
产品信息
PA5-64326
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein corresponding to Human BHLHB5
偶联物
形式
Liquid
浓度
0.1 mg/mL
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
Immunogen sequence: GLLVGSAGVG GDPSLSSLPA GAALCLKYGE SASRGSVAES SGGEQSPDDD SDGRCELVLR AGV
Highest antigen sequence identity to the following orthologs: Mouse - 95%, Rat - 94%.
靶标信息
BHLHB5 inhibits DNA binding of TCF3/E47 homodimers and TCF3 (E47)/NEUROD1 heterodimers and acts as a strong repressor of Neurod1 and Myod-responsive genes, probably by heterodimerization with class a basic helix-loop-helix factors. BHLHB5 despite the presence of an intact basic domain, does not bind to DNA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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