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Invitrogen
BIT1 Polyclonal Antibody
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产品信息
PA1-27578
产品规格
宿主/亚型
Chicken
/ IgY
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to human CDNA FLJ32471 fis. clone SKNMC2000322. weakly similar to MAJOR CENTROMERE AUTOANTIGEN B.
偶联物
形式
Liquid
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
产品详细信息
PA1-27578 detects BIT1 from human samples.
PA1-27578 may be successfully used in Western blot applications. By Western blot, this antibody has only been tested on fusion protein.
The PA1-27542 immunogen is a synthetic peptide corresponding to human CDNA FLJ32471 fis. clone SKNMC2000322. weakly similar to MAJOR CENTROMERE AUTOANTIGEN B.
靶标信息
The protein encoded by this gene is a mitochondrial protein with two putative domains, an N-terminal mitochondrial localization sequence, and a UPF0099 domain. In vitro assays suggest that this protein possesses peptidyl-tRNA hydrolase activity, to release the peptidyl moiety from tRNA, thereby preventing the accumulation of dissociated peptidyl-tRNA that could reduce the efficiency of translation. This protein also plays a role regulating cell survival and death. It promotes survival as part of an integrin-signaling pathway for cells attached to the extracellular matrix characterized by intellectual disability, postnatal microcephaly, progressive cerebellar atrophy, hearing impairment, polyneuropathy, failure to thrive, and organ fibrosis with exocrine pancreas insufficiency. Alternative splicing results in multiple transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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