Search

  • 联系我们
  • 货号直购

Alomone Labs, LTD

BMPR1A (extracellular) Polyclonal Antibody

查看其他12个BMPR1A抗体

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}

{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}

说明书
Certificates
实验方案
问题与答案
技术支持
说明书
Certificates
实验方案
问题与答案
技术支持
说明书
Certificates
实验方案
问题与答案
技术支持
Additional Information:
{{banner.description}}
{{$ctrl.isSkuNotesCollapsed ? 'View more' : 'View less'}}
BMPR1A (extracellular) Polyclonal Antibody

产品信息

ABR-043-200UL

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1:200
-

免疫组化（冰冻） (IHC (F))

1:300
-

免疫细胞化学 (ICC/IF)

Assay-dependent
-

流式细胞分析 (Flow)

5 µg
-
产品规格

种属反应

Human, Mouse, Rat

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Peptide APVHRDWRVHLALD, corresponding to amino acid residues 291-304 of mouse GPR142. Extracellular, 3rd loop.
3D表位/免疫原

偶联物

Unconjugated Unconjugated Unconjugated

形式

Lyophilized

浓度

0.8 mg/mL

规格

160 µg

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.4, with 1% BSA

内含物

0.05% sodium azide

保存条件

-20°C, Avoid Freeze/Thaw Cycles

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

Immunogen sequence: APVHRDWRVHLALD

Reconstitution: 50 uL double distilled water (DDW). The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).

靶标信息

BMPR1A is a Type I member of the TGF beta receptor superfamily of transmembrane ser/thr kinases which phosphorylates intracellular SMADs in response to bone morphogenic proteins. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
引用该产品

生物信息学

蛋白别名: Activin receptor-like kinase 3; ALK-3; BMP type-1A receptor; BMP-2/BMP-4 receptor; BMPR-1A; BMPRIA; Bone morphogenetic protein 4 receptor; Bone morphogenetic protein receptor type-1A; bone morphogenetic protein receptor, type 1A; CD292; Serine/threonine-protein kinase receptor R5; SKR5

查看更多 收起

基因别名: 1110037I22Rik; ACVRLK3; ALK3; AU045487; Bmpr; BMPR-IA; BMPR1A

查看更多 收起

UniProt ID: (Rat) Q78EA7, (Mouse) P36895

查看更多 收起

Entrez Gene ID: (Rat) 81507, (Mouse) 12166

查看更多 收起

功能
RNA polymerase II transcription factor activity, sequence-specific DNA binding molecular_function protein serine/threonine kinase activity receptor signaling protein serine/threonine kinase activity transforming growth factor beta-activated receptor activity ATP binding protein homodimerization activity SMAD binding metal ion binding nucleotide binding glycoprotein binding protein kinase activity transmembrane receptor protein serine/threonine kinase activity kinase activity transferase activity transferase activity, transferring phosphorus-containing groups serine/threonine protein kinase receptor
参与通路
in utero embryonic development mesoderm formation somitogenesis Mullerian duct regression regulation of endothelial cell proliferation positive regulation of mesenchymal cell proliferation heart morphogenesis endocardial cushion formation transcription from RNA polymerase II promoter protein phosphorylation immune response pattern specification process ectoderm development nervous system development endoderm development heart development biological_process dorsal/ventral axis specification anterior/posterior pattern specification dorsal/ventral pattern formation positive regulation of pathway-restricted SMAD protein phosphorylation neural crest cell development stem cell population maintenance pituitary gland development neural plate mediolateral regionalization signal transduction by protein phosphorylation cell differentiation lung development positive regulation of bone mineralization BMP signaling pathway hindlimb morphogenesis odontogenesis of dentin-containing tooth embryonic digit morphogenesis regulation of endothelial cell differentiation positive regulation of osteoblast differentiation positive regulation of transcription, DNA-templated paraxial mesoderm development paraxial mesoderm structural organization lateral mesoderm development regulation of lateral mesodermal cell fate specification mesendoderm development embryonic organ development developmental growth embryonic morphogenesis positive regulation of epithelial cell proliferation negative regulation of neurogenesis cartilage development palate development positive regulation of SMAD protein import into nucleus neural plate pattern specification heart formation regulation of cellular senescence chondrocyte differentiation transmembrane receptor protein serine/threonine kinase signaling pathway phosphorylation
guarantee_icon

性能保障

只要您发现Invitrogen抗体在实验中的表现与网站或说明书的所述内容不符，您即可享受免费退换货服务。*

了解更多
help_icon

随时为您服务

获取常见问题的专家解答，或者直接联系我们的技术专家，咨询应用、设备、常规产品使用问题。

联系技术支持