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Invitrogen
BNIP3 Polyclonal Antibody, DyLight™ 488
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产品信息
PA5-22861
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide against an N-terminal region (within residues 1-50) of the human BNIP3 protein.
偶联物
激发/发射光谱
492/519 nm
查看光谱
形式
Liquid
浓度
1 mg/mL
保存条件
4°C, store in dark
运输条件
Wet ice
RRID
产品详细信息
In Western blot a band is seen in hypoxic samples at ~30 and 60 kDa, representing the BNIP3 protein.
There are some non-specific bands present as well.
It is recommended that normoxic samples are run next to the hypoxic samples as a negative control.
靶标信息
NIP3 is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. NIP3 contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein is known to induce apoptosis, even in the presence of BCL2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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