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Abnova
BRDG1 Monoclonal Antibody (5A10)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00026228-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
5A10
抗原
BRDG1 (NP_036240, 186 a.a. approximately 293 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
Immunogen sequence: EATEMLQKNP SLGNMILRPG SDSRNYSITI RQEIDIPRIK HYKVMSVGQN YTIELEKPVT LPNLFSVIDY FVKETRGNLR PFICSTDENT GQEPSMEGRS EKLKKNPH
靶标信息
The protein encoded by this gene functions as a docking protein acting downstream of Tec tyrosine kinase in B cell antigen receptor signaling. The protein is directly phosphorylated by Tec in vitro where it participates in a postive feedback loop, increasing Tec activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BCR downstream-signaling protein 1; docking protein BRDG1; stem cell adaptor protein 1; unnamed protein product
基因别名: BRDG1; STAP-1
UniProt ID: (Human) Q9ULZ2
Entrez Gene ID: (Human) 26228
phosphotyrosine binding
transmembrane receptor protein tyrosine kinase adaptor activity
macrophage colony-stimulating factor receptor binding
protein binding
phospholipid binding
protein kinase binding
protein tyrosine kinase activator activity
protein binding, bridging
receptor tyrosine kinase binding
signaling adaptor activity
transmembrane receptor protein tyrosine kinase signaling pathway
positive regulation of gene expression
negative regulation of macrophage chemotaxis
positive regulation of B cell receptor signaling pathway
positive regulation of phagocytosis, engulfment
cellular response to lipopolysaccharide
negative regulation of ruffle assembly
negative regulation of macrophage colony-stimulating factor signaling pathway
positive regulation of microglial cell activation
negative regulation of microglial cell migration
positive regulation of microglial cell mediated cytotoxicity
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
