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Invitrogen
BRG1 Polyclonal Antibody
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BRG1 Antibody (PA5-81261) in ICC/IF
Immunofluorescence staining of SMARCA4 in HeLa cells. Cells were fixed with 4% PFA, blocked with 10% serum, and incubated with BRG1 Polyclonal Antibody (Product # PA5-81261) (1:5000) at 4° C overnight. Then cells were stained with the Alexa Fluor 594-conjugated Goat Anti-rabbit IgG secondary antibody (red). Positive staining was localized to nucleus.
产品信息
PA5-81261
应用
建议稀释比
已发表文章
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to the N-terminus of the Human SMARCA4/BRG1
偶联物
形式
Liquid
浓度
Lot-Specific
保存条件
Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
运输条件
Wet ice
RRID
产品详细信息
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human BRG1.
靶标信息
Brg1 (Brahma-related gene 1) is an ATPase subunit of SWI2/SNF2-like chromatin-remodeling complexes that enable access of regulatory and effector proteins in transcription, DNA repair and DNA replication. Although Brg1-containing complexes are not essential for general cell survival, they participate in transcriptional regulation of several hundred genes including those involved in interferon and stress response, immune cells differentiation, neurogenesis, cell cycle etc. and is absolutely necessary for mouse embryogenesis. Brg1 is also involved in cell growth arrest, senescence and tumour supression.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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