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Invitrogen
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: KLLLYDTLQG ELQERIQRLE EDRQSLDLSS EWWDDKLHAR GSSRSWDSLP PSKRKKAPLV SGPYIVYMLQ EIDILEDWTA IKKARAAVSP QK
Highest antigen sequence indentity to the following orthologs: Mouse - 89%, Rat - 93%.
This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。