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Invitrogen
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Immunogen sequence: SLAGDEATHH TEDAAEEERL VLLENQKHLP VEEQLKLLLE RLDEVNASKQ SVGRSRRAKM IKKEMTALRR KLAHQRETGR DGPERHGPSS RGSLTPHPAA CDKDGQTD
Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 94%.
BRPF1 (peregrin) is a component of the MOZ/MORF complex. This complex has histone H3 acetyltransferase activity. BRPF1 preferentially mediates histone H3-K23 acetylation and positively regulates the transcription of RUNX1 and RUNX2. Mutations affecting the gene can result in intellectual developmental disorder with dysmorphic facies and ptosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Bromodomain and PHD finger-containing protein 1; bromodomain-containing protein, 140kD; Peregrin; Protein Br140
基因别名: BR140; BRPF1
UniProt ID: (Human) P55201
Entrez Gene ID: (Human) 7862