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Invitrogen
BTN2A2 Polyclonal Antibody
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产品信息
PA5-47670
产品规格
种属反应
Mouse
宿主/亚型
Sheep
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Mouse myeloma cell line NS0-derived recombinant mouse BTN2A2/Butyrophilin 2 Gln29-Ser219
偶联物
形式
Lyophilized
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 5% trehalose
内含物
No Preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
In direct ELISAs and Western blots, less than 10% cross-reactivity with recombinant mouse (rm) BTN and rmBTNL2 is observed.
Reconstitute at 0.2 mg/mL in sterile PBS.
靶标信息
Butyrophilin is the major protein associated with fat droplets in the milk. This gene is a member of the BTN2 subfamily of genes, which encode proteins belonging to the butyrophilin protein family. The gene is located in a cluster on chromosome 6, consisting of seven genes belonging to the expanding B7/butyrophilin-like group, a subset of the immunoglobulin gene superfamily. The encoded protein is a type I receptor glycoprotein involved in lipid, fatty-acid and sterol metabolism. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: butyrophilin 2; Butyrophilin subfamily 2 member A2
基因别名: Btn2; Btn2a2; D030063K05
UniProt ID: (Mouse) A4QPC6
Entrez Gene ID: (Mouse) 238555
negative regulation of phosphatidylinositol 3-kinase signaling
negative regulation of cellular metabolic process
positive regulation of regulatory T cell differentiation
negative regulation of activated T cell proliferation
negative regulation of cytokine secretion
negative regulation of T cell receptor signaling pathway
negative regulation of protein kinase B signaling
negative regulation of ERK1 and ERK2 cascade
negative regulation of G1/S transition of mitotic cell cycle
