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Invitrogen
Brevican Polyclonal Antibody
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产品信息
PA1-31195
产品规格
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic C terminal peptide for particulate guanylyl cyclase B. (unfortunately, the amino acid sequence is considered to be commercially sensitive). All peptides were amidated for conjugation.
偶联物
形式
Liquid
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Wet ice
RRID
产品详细信息
PA1-31195 detects PGCB from human, rat samples.
PA1-31195 has been successfully used in Western blot applications.
The PA1-31195 immunogen is: Synthetic C terminal peptide for particulate guanylyl cyclase B. (unfortunately, the amino acid sequence is considered to be commercially sensitive). All peptides were amidated for conjugation.
靶标信息
Brevican is the most abundant chondroitin sulfate proteoglycan in the extracellular matrix of the adult brain. It is a member of the lectican family of aggregating extracellular matrix proteoglycans that bear chondroitin sulfate (CS) chains. It is highly expressed in the central nervous system and is thought to stabilize synapses and inhibit neural plasticity. Brevican is secreted from astrocytes and neurons as a 145 kD core protein that bears up to three, covalently-linked, CS chains. It is also is secreted as a 145 kD core protein without CS chains. When cleaved by extracellular glutamyl endopeptidases, the ADAMTSs, a 55 kD N-terminal fragment is formed that contains the unique C terminal epitope EAMESE.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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