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Progen
Butyrophilin Monoclonal Antibody (102.43)
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产品信息
651153
应用
建议稀释比
已发表文章
产品规格
种属反应
Bovine,
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
102.43
抗原
Butyrophilin Purified From Bovine Milk Fat Globule Membrane
偶联物
形式
Liquid
浓度
Conc. Not Determined
内含物
0.09% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Recognizes butyrophilin, a unique 67 kD polypeptide present in lactating mammary gland epithelium and in the milk fat globule membrane (MFGM). No cross-reaction with other MFGM proteins. The epitope has been localized on the N-terminal extracellular part of the protein, close to the transmembrane region. Butyrophilins have recently been described as a new family of immunoregulators, similar to the co-stimulatory and co-inhibitory family of B7 molecules. Polypeptide reacting: Butyrophilin, 67 kD polypeptide; present in the apical membrane of lactating mammary epithelium and in MFGM.Reactivity on cultured cell lines: Transfected cell line BMGE with butyrophilin cDNA.Positive control: Milk fat globule membrane (MFGM).
靶标信息
BTN1A1 (Butyrophilin) is the major protein associated with fat droplets in the milk. It is a member of the immunoglobulin superfamily. It may have a cell surface receptor function. The human butyrophilin gene is localized in the major histocompatibility complex (MHC) class I region of 6p and may have arisen relatively recently in evolution by the shuffling of exons between 2 ancestral gene families.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: bK14H9.2 (butyrophilin, subfamily 1, member A1); BT; Butyrophilin subfamily 1 member A1; butyrophilin, subfamily 1, member A1
基因别名: BT; BTN; BTN1; BTN1A1
UniProt ID: (Human) Q13410, (Bovine) P18892
Entrez Gene ID: (Human) 696, (Bovine) 282157
