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Invitrogen
C/EBP gamma Recombinant Rabbit Monoclonal Antibody (001)
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产品信息
MA5-30278
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
001
抗原
Recombinant Human CEBPG/CEBP gamma Protein (Pro39-Asn147)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
This antibody has specificity for Human CEBPG/CEBP gamma.
靶标信息
The C/EBP family of transcription factors regulates viral and cellular CCAAT/enhancer element-mediated transcription. C/EBP proteins contain the bZIP region, which is characterized by two motifs in the C-terminal half of the protein: a basic region involved in DNA binding and a leucine zipper motif involved in dimerization. The C/EBP family consist of several related proteins, C/EBP alpha, C/EBP beta, C/EBP gamma, and C/EBP delta, that form homodimers and that form heterodimers with each other. CCAAT/enhancer binding protein gamma may cooperate with Fos to bind PRE-I enhancer elements.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C EBP; C/EBP gamma; CCAAT/enhancer binding protein (C/EBP), gamma; CCAAT/enhancer-binding protein gamma; CEBP gamma
基因别名: CEBPG; GPE1BP; IG/EBP-1
UniProt ID: (Human) P53567
Entrez Gene ID: (Human) 1054
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
DNA binding
protein binding
transcription factor binding
protein homodimerization activity
sequence-specific DNA binding
RNA polymerase II core promoter proximal region sequence-specific DNA binding, bending
protein heterodimerization activity
basic leucine zipper transcription factor
liver development
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
immune response
mRNA metabolic process
B cell differentiation
natural killer cell mediated cytotoxicity
enucleate erythrocyte differentiation
positive regulation of DNA binding
negative regulation of sequence-specific DNA binding transcription factor activity
positive regulation of interferon-gamma biosynthetic process
positive regulation of DNA repair
positive regulation of transcription from RNA polymerase II promoter
positive regulation of sequence-specific DNA binding transcription factor activity
