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This gene encodes a protein that regulates thymic epithelial cell proliferation and thymus size. It has been identified as a ligand for the class I human leukocyte antigen (HLA-I) in thymus. Studies of the orthologous mouse protein suggest that it may also play a role in spermatid differentiation, as well as in neuronal morphogenesis and synaptic plasticity. Polymorphisms in this gene are associated with susceptibility for multiple sclerosis (MS). Alternative splicing results in multiple transcript variants.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Protein SPATIAL; Protein TBATA; Stromal protein associated with thymii and lymph node; Stromal protein associated with thymii and lymph node homolog; stromal protein associated with thymii and lymph nodes; thymus and testis specific nuclear protein; thymus, brain and testes associated; Thymus, brain and testes-associated protein
基因别名: 1700021K02Rik; AI428928; C10orf27; RGD1561665; SPATIAL; TBATA; Titest
UniProt ID: (Human) Q96M53, (Mouse) Q7TSD4
Entrez Gene ID: (Human) 219793, (Rat) 499429, (Mouse) 65971