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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
The TTC40 gene, which stands for Tetratricopeptide repeat domain 40, is a member of the TPR protein family characterized by highly conserved motifs that facilitate protein-protein interactions. This gene plays a significant role in various cellular processes, including signal transduction and protein assembly. TTC40 has been identified as a novel methylated gene in nasopharyngeal carcinoma, where its expression is significantly reduced in tumor tissues due to hypermethylation. This epigenetic alteration suggests a potential role of TTC40 in tumorigenesis, possibly acting as a tumor suppressor. The decreased expression of TTC40 in cancerous tissues highlights its importance in maintaining cellular homeostasis and integrity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: cilia and flagella protein 46; tetratricopeptide repeat domain 40; tetratricopeptide repeat protein 40; TPR repeat-containing protein C10orf93; unnamed protein product
基因别名: 9330101J02Rik; AABR07005985.1; bA288G11.4; bA288G11.5; bB137A17.2; bB137A17.3; C10orf123; C10orf124; C10orf92; C10orf93; E030019B06Rik; Gm170; RGD1559985; TTC40
UniProt ID: (Human) Q8IYW2
Entrez Gene ID: (Human) 54777, (Rat) 499282, (Mouse) 212124