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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: HTAFTKHSEEL GTEEGEVEEM DTLDPQTGLF YRSALTQSQS AKQQKLSQPP LEQTQLQVKT LQCFQTKQKQ TIHLQADQLQ HKLPQMPQLS IRHQKLTPLQ QEQAQPKPDV QHTQHPMVAK DRQLPTLMAQ PPQTVVQVLA VKTTQQL
Highest antigen sequence identity to the following orthologs - mouse 95%, rat 95%.
EMSY is a regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2. As part of a histone H3-specific methyltransferase complex may mediate ligand-dependent transcriptional activation by nuclear hormone receptors. Diseases associated with EMSY include Sporadic Breast Cancer and Breast Cancer.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: EMSY protein; EMSY, BRCA2 interacting transcriptional repressor; FLJ90741; protein EMSY; unnamed protein product
基因别名: C11orf30; GL002
UniProt ID: (Human) Q7Z589
Entrez Gene ID: (Human) 56946