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Invitrogen
PLEKHG7 Polyclonal Antibody
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产品信息
PA5-71021
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
synthetic peptide directed towards the N-terminal region of human C12orf74
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This target displays homology in the following species: Horse: 100%; Human: 100%; Rabbit: 86%
靶标信息
The PLEKHG7 gene (Pleckstrin Homology and RhoGEF Domain Containing G7) encodes a protein that is a member of the Rho guanine nucleotide exchange factor (RhoGEF) family. This protein is involved in the regulation of the Rho family of GTPases, which play a critical role in multiple cellular processes including cytoskeletal organization, cell migration, and cell proliferation. The pleckstrin homology (PH) domain of PLEKHG7 allows it to interact with phosphoinositides, which helps localize the protein to cellular membranes where it can activate Rho GTPases. Dysregulation of PLEKHG7 has been implicated in certain cancers, highlighting its importance in cell signaling and cancer biology.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: PH domain-containing family G member 7; pleckstrin homology domain containing, family G (with RhoGef domain) member 7; Pleckstrin homology domain-containing family G member 7
基因别名: C12orf74; PLEKHG7
UniProt ID: (Human) Q6ZR37
Entrez Gene ID: (Human) 440107
