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Proteintech
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Immunogen sequence: MVSQSTVRQ DSPVEPWEGI SDHSGIIDGS PRLLNTDHPP CQLDIRLMRH KAVWINPQDV QQQPQDLQSQ VPAAGNSGTH FVTDAASPSG PSPSCLGDSL AETTLSEDTT DSVGSASPHG SSEKSSSFSL SSTEVHMVRP GYSHRVSLPT SPGILATSPY PETDSAFFEP SHLTSAADEG AVQVSRRTIS SNSFSPEVFV LPVDVEKENA HFYVADMIIS AMEKMKCNIL SQQQTESWSK EVSGLLGSDQ PDSEMTFDTN IKQESGSSTS SYSGYEGCAV LQVSPVTETR TYHDVKEICK CDVDEFV (1-306 aa encoded by BC032311)
This gene encodes a cysteine-rich protein that contains a putative zinc-RING and/or ribbon domain. The encoded protein is related to Run domain Beclin-1-interacting and cysteine-rich domain-containing protein, which plays a role in endocytic trafficking and autophagy. In cervical cancer cell lines, this gene is expressed at low levels and may function as a tumor suppressor. Promoter hypermethylation of this gene is observed in cervical cancer cell lines and tissue derived from human patients.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: KIAA0226-like; Pacer; Protein associated with UVRAG as autophagy enhancer; Protein Rubicon-like
基因别名: C13orf18; KIAA0226L; RUBCNL
UniProt ID: (Human) Q9H714
Entrez Gene ID: (Human) 80183