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Invitrogen
C14orf21 Polyclonal Antibody
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产品信息
PA5-31719
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human C14orf21. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 1% BSA, 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: A549.
Predicted reactivity: Mouse (80%), Rat (83%), Rhesus Monkey (98%), Bovine (88%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The C14orf21 gene, also known as SLIRP (SRA stem-loop interacting RNA binding protein), is located on chromosome 14 and encodes a mitochondrial protein involved in RNA processing. SLIRP is crucial for the stabilization and regulation of mitochondrial-encoded RNAs, which play a vital role in mitochondrial gene expression and overall mitochondrial function. The SLIRP protein interacts with RNA stem-loop structures, particularly those involved in the steroid receptor RNA activator (SRA), thereby regulating gene expression by modulating the activity of nuclear receptors. Defects in SLIRP can lead to impaired mitochondrial function, resulting in various clinical manifestations, including mitochondrial myopathy and other disorders related to mitochondrial dysfunction.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: NOP9 nucleolar protein homolog; Nucleolar protein 9; pumilio domain-containing protein C14orf21
基因别名: C14orf21; KIAA2021; NOP9
UniProt ID: (Human) Q86U38
Entrez Gene ID: (Human) 161424
