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Proteintech
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Immunogen sequence: MAAPEAPPL DRVFRTTWLS TECDSHPLPP SYRKFLFETQ EADLAGGTTV AAGNLLNESE KDCGQDRRAP GVQPCLLVTM TSVVKTVYSL QPSSALSGGQ PADTQTRATS KSLLPVRSKE VDVSKQLHSG GPENDVTKIT KLRRENGQMK ATDTATRRNV RKGYKPLSKQ KSEEELKDKN QLLEAVNKQL HQKLTETQGE LKDLTQKVEL LEKFRDNCLA ILESKGLDPA LGGETLASRQ ESTTDHMDSM LLLETLQEEL KLFNETAKKQ MEELQALKVK LEMKEERVRF LEQQTLCNNQ VNDLTTALKE MEQLLEM (1-316 aa encoded by BC118639)
C15orf23 is an essential component of the mitotic spindle required for faithful chromosome segregation and progression into anaphase. It promotes the metaphase-to-anaphase transition and is required for chromosome alignment, normal timing of sister chromatid segregation, and maintenance of spindle pole architecture. The astrin (SPAG5)-kinastrin (SKAP) complex promotes stable microtubule-kinetochore attachments.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Kinastrin; Kinetochore-localized astrin-binding protein; kinetochore-localized astrin/SPAG5 binding protein; Kinetochore-localized astrin/SPAG5-binding protein; putative TRAF4-associated factor 1; SKAP; small kinetochore associated protein; Small kinetochore-associated protein; small kinetochore-associated protein, kinetochore-localized astrin-binding protein, TRAF4 associated factor 1; TRAF4 associated factor 1; TRAF4-associated factor 1
基因别名: C15orf23; HSD11; KNSTRN; SKAP; TRAF4AF1
UniProt ID: (Human) Q9Y448
Entrez Gene ID: (Human) 90417