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Proteintech
C1QBP Polyclonal Antibody, CoraLite® 594
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产品信息
CL594-24474
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
C1QBP fusion protein Ag19773
偶联物
CoraLite® 594
CoraLite® 594
CoraLite® 594
激发/发射光谱
593/614 nm
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 0.5% BSA, 50% glycerol
内含物
0.05% ProClin 300
保存条件
-20°C, store in dark
运输条件
Wet ice
产品详细信息
Immunogen sequence: MLPLLRCVP RVLGSSVAGL RAAAPASPFR QLLQPAPRLC TRPFGLLSVR AGSERRPGLL RPRGPCACGC GCGSLHTDGD KAFVDFLSDE IKEERKIQKH KTLPKMSGGW ELELNGTEAK LVRKVAGEKI TVTFNINNSI PPTFDGEEEP SQGQKVEEQE PELTSTPNFV VEVIKNDDGK KALVLDCHYP EDEVGQEDEA ESDIFSIREV SFQSTGESEW KDTNYTLNTD SLDWALYDHL MDFLADRGVD NTFADELVEL STALEHQEYI TFLEDLKSFV KSQ
靶标信息
Replication Protein A (RPA) (also known as human single-stranded DNA binding protein, or HSSB) is involved in DNA replication, repair, and recombination. RPA from human cells is a stable heterotrimer of 70kDa, 32-34kDa, and 11-14kDa subunits (RPA70, RPA32, and RPA14 respectively). RPA is required for the SV40 large tumor antigen-catalyzed unwinding of SV40 DNA and stimulates DNA polymerase alpha and delta. RPA34 is phosphorylated at the G1/S boundary of the cell cycle or upon exposure of cells to DNA damage-inducing agents including ionizing and UV radiation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ASF/SF2-associated protein p32; C1q globular domain-binding protein; C1qBP; Complement component 1 Q subcomponent-binding protein, mitochondrial; complement component 1, q subcomponent binding protein; GC1q-R protein; Glycoprotein gC1qBP; Hyaluronan-binding protein 1; Mitochondrial matrix protein p32; p33; RPA; SF2AP32; splicing factor SF2-associated protein; unnamed protein product
基因别名: AA407365; AA986492; C1QBP; COXPD33; D11Wsu182e; gC1Q-R; GC1QBP; gC1qR; HABP1; P32; SF2AP32; SF2P32
UniProt ID: (Human) Q07021, (Rat) O35796
Entrez Gene ID: (Human) 708, (Rat) 29681, (Mouse) 12261
complement component C1q binding
transcription corepressor activity
mRNA binding
enzyme inhibitor activity
protein kinase C binding
protein binding
hyaluronic acid binding
transcription factor binding
kininogen binding
adrenergic receptor binding
deoxyribonuclease inhibitor activity
C5-methylcytidine-containing RNA reader activity
mitochondrial ribosome binding
negative regulation of transcription from RNA polymerase II promoter
transcription, DNA-templated
mRNA processing
apoptotic process
immune response
complement activation, classical pathway
RNA splicing
phosphatidylinositol 3-kinase signaling
regulation of complement activation
negative regulation of interferon-gamma production
negative regulation of interleukin-12 production
negative regulation of MDA-5 signaling pathway
negative regulation of RIG-I signaling pathway
mature ribosome assembly
positive regulation of apoptotic process
innate immune response
positive regulation of cell adhesion
negative regulation of mRNA splicing, via spliceosome
negative regulation of defense response to virus
positive regulation of protein kinase B signaling
positive regulation of mitochondrial translation
positive regulation of neutrophil chemotaxis
positive regulation of substrate adhesion-dependent cell spreading
positive regulation of trophoblast cell migration
positive regulation of dendritic cell chemotaxis
immune system process
regulation of transcription, DNA-templated
ribosome biogenesis
double-strand break repair via homologous recombination
mitochondrial RNA catabolic process
adaptive immune response
cellular response to DNA damage stimulus
protein kinase B signaling
negative regulation of double-strand break repair via homologous recombination
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