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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: GRGRGMIGRG RGGFGGRGRG RGRGRGALAR PVLTKEQLDN QLDAYMSKTK GHLDAELDAY MAQTDPETND
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%.
CHTOP is a small nuclear protein that is characterized by an arginine and glycine rich region. This protein may have an important role in the regulation of fetal globin gene expression and in the activation of estrogen-responsive genes. A recent study reported that this protein binds 5-hydroxymethylcytosine (5hmC) and associates with an arginine methyltransferase complex (methylosome), which promotes methylation of arginine 3 of histone H4 (H4R3) and activation of genes involved in glioblastomagenesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: DKFZP547E1010; Friend of Prmt1; friend of PRMT1 protein; RP1-178F15.2; small protein rich in arginine and glycine
基因别名: C10orf77; C1orf77; FL-SRAG; FOP; pp7704; SRAG; SRAG-3; SRAG-5
UniProt ID: (Human) Q9Y3Y2
Entrez Gene ID: (Human) 26097