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Proteintech
C1orf86 Polyclonal Antibody
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产品信息
26138-1-AP
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
C1orf86 Fusion Protein Ag23534 (1-195 aa encoded by BC103992)
偶联物
形式
Liquid
浓度
0.19 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MEAARRPRL GLSRRRPPPA GGPSGGRPWF LLGGDERERL WAELLRTVSP ELILDHEVPS LPAFPGQEPR CGPEPTEVFT VGPKTFSWTP FPPDLWGPGR SYRLLHGAGG HLESPARSLP QRPAPDPCRA PRVEQQPSVE GAAALRSCPM CQKEFAPRLT QLDVDSHLAQ CLAESTEDVT CLSWMCKTLN DPGSQG (1-195 aa encoded by B C103992)
靶标信息
C1orf86 is a component of the Fanconi anemia (FA) complex required to recruit the FA complex to DNA interstrand cross-links (ICLs) and promote ICLs repair. Following DNA damage recognizes and binds 'Lys-63'-linked ubiquitin generated by RNF8 at ICLs and recruits other components of the FA complex. It promotes translesion synthesis via interaction with REV1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: FANCA-associated protein of 20 kDa; Fanconi anemia core complex-associated protein 20; Fanconi anemia-associated protein of 20 kDa
基因别名: C1orf86; FAAP20; FP7162
UniProt ID: (Human) Q6NZ36
Entrez Gene ID: (Human) 199990
