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PA1-20844 detects C1q in human samples.
PA1-20844 has been successfully used in ELISA and Western blot procedures. Predicted molecular weight by western blot is 26 kDa. Possible positive controls for this product are human plasma Clq protein.
The PA1-20844 immunogen is Full length plasma C1q protein (Human).
C1q is a sub-component of complement C1. C1q associates with complement components C1r and C1s, which are required for the progression of the proteolytic complement cascade. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。