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PA5-16601 targets C1q Complement in IF applications and shows reactivity with Human samples.
The PA5-16601 immunogen is c1q component isolated from human serum.
C1q is a sub-component of complement C1. C1q associates with complement components C1r and C1s, which are required for the progression of the proteolytic complement cascade. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1.
仅用于科研。不用于诊断过程。未经明确授权不得转售。