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Proteintech
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Immunogen sequence: MCIIFFKFD PRPVSKNAYR LILAANRDEF YSRPSKLADF WGNNNEILSG LDMEEGKEGG TWLGISTRGK LAALTNYLQP QLDWQARGRG ELVTHFLTTD VDSLSYLKKV SMEGHLYNGF NLIAANLSTA KGDVICYYGN RGEPDPIVLT PGTYGLSNAL LETPWRKLCF GKQLFLEAVE RSQALPKDVL IASLLDVLNN KEAQLPDPAI EDQGGEYVQP MLSKYAAVCV RCPGYGTRTN TIILVDADGH VTFTERSMMD KDLSHWETRT YEFTLQS (1-276 aa encoded by BC041339)
This gene belongs to the transport and Golgi organization family, whose members are predicted to play roles in secretory protein loading in the endoplasmic reticulum. Depletion of this gene in Drosophila S2 cells causes fusion of the Golgi with the ER. In mouse tissue culture cells, this protein co-localizes with a mitochondrially targeted mCherry protein and displays very low levels of co-localization with Golgi and peroxisomes. Allelic variants of this gene are associated with rhabdomyolysis, metabolic crises with encephalopathy, and cardiac arrhythmia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Ser/Thr-rich protein T10 in DGCR region; Transport and Golgi organization 2 homolog; Transport and Golgi organization protein 2 homolog
基因别名: C22orf25; D16H22S680E; MECRCN; T10; TANGO2
UniProt ID: (Human) Q6ICL3, (Mouse) P54797
Entrez Gene ID: (Human) 128989, (Mouse) 27883