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Bioss
C22orf32 Polyclonal Antibody
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产品信息
BS-15136R
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
KLH conjugated synthetic peptide derived from human C22orf32, amino acids 1-60.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA
内含物
0.02% ProClin 300
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Essential regulatory subunit of the mitochondrial calcium uniporter complex (uniplex), a complex that mediates calcium uptake into mitochondria (PubMed:24231807, PubMed:26774479, PubMed:27099988). Required to bridge the calcium-sensing proteins MICU1 and MICU2 with the calcium-conducting subunit MCU (PubMed:24231807). Plays a central role in regulating the uniplex complex response to intracellular calcium signaling (PubMed:27099988). Acts by mediating activation of MCU and retention of MICU1 to the MCU pore, in order to ensure tight regulation of the uniplex complex and appropriate responses to intracellular calcium signaling (PubMed:27099988).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Essential MCU regulator, mitochondrial; single-pass membrane protein with aspartate-rich tail 1; Single-pass membrane protein with aspartate-rich tail 1, mitochondrial; UPF0466 protein C22orf32 homolog, mitochondrial; UPF0466 protein C22orf32, mitochondrial
基因别名: 1500032L24Rik; C22orf32; DDDD; dJ186O1.1; EMRE; RGD1311310; SMDT1
UniProt ID: (Human) Q9H4I9, (Mouse) Q9DB10
Entrez Gene ID: (Human) 91689, (Rat) 315166, (Mouse) 69029
