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Proteintech
C8orf4 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
26279-1-AP
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
C8orf4 Fusion Protein Ag23930 (1-106 aa encoded by BC021672)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.35 mg/mL
规格
52.5 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MKAKRSHQA IIMSTSLRVS PSIHGYHFDT ASRKKAVGNI FENTDQESLE RLFRNSGDKK AEERAKIIFA IDQDVEEKTR ALMALKKRTK DKLFQFLKLR KYSIKVH (1-106 aa encoded by BC021672)
靶标信息
This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: human thyroid cancer 1; protein C8orf4; protein C8orf4 homolog; thyroid cancer protein 1; thyroid cancer-1; unnamed protein product
基因别名: 1110065B09Rik; 1810011O10Rik; C8orf4; TC-1; TC1
UniProt ID: (Human) Q9NR00, (Mouse) Q9D915
Entrez Gene ID: (Human) 56892, (Mouse) 69068
endothelial cell activation involved in immune response
regulation of transcription, DNA-templated
cellular response to heat
negative regulation of Notch signaling pathway
positive regulation of NIK/NF-kappaB signaling
regulation of cell cycle G1/S phase transition
negative regulation of apoptotic process
regulation of hemopoiesis
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
