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Invitrogen
CABC1 Polyclonal Antibody
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CABC1 Antibody (PA5-29125) in ICC/IF
CABC1 Polyclonal Antibody detects CABC1 protein at mitochondria by immunofluorescent analysis. Sample: MCF-7 cells were fixed in ice-cold MeOH for 5 min. Green: CABC1 protein stained by CABC1 Polyclonal Antibody (Product # PA5-29125) diluted at 1:500. Blue: Hoechst 33342 staining.
产品信息
PA5-29125
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human CABC1. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.53 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: NT2D1, IMR32, mouse heart.
Predicted reactivity: Mouse (94%), Rat (93%), Rhesus Monkey (99%), Bovine (96%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
ADCK3 serine/threonine kinase is a mitochondrial protein similar to yeast ABC1 that is a member of the ADCK family. CABC1 encodes a mitochondrial protein similar to yeast ABC1, which functions in an electron-transferring membrane protein complex in the respiratory chain. It is not related to the family of ABC transporter proteins. Expression of this gene is induced by the tumor suppressor p53 and in response to DNA damage, and inhibiting its expression partially suppresses p53-induced apoptosis. Alternatively spliced transcript variants have been found.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: aarF domain containing kinase 3; aarF domain-containing protein kinase 3; atypical kinase ADCK3, mitochondrial; Atypical kinase COQ8A, mitochondrial; Chaperone activity of bc1 complex-like; chaperone activity of bc1 complex-like, mitochondrial; chaperone, ABC1 activity of bc1 complex homolog; chaperone, ABC1 activity of bc1 complex like; Chaperone-ABC1-like; Coenzyme Q protein 8A; coenzyme Q8 homolog
基因别名: 4632432J16Rik; ADCK3; AI462003; ARCA2; CABC1; COQ10D4; COQ8; COQ8A; mKIAA0451; PP265; SCAR9
UniProt ID: (Mouse) Q60936, (Human) Q8NI60
Entrez Gene ID: (Mouse) 67426, (Human) 56997
