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Abnova
CABYR Polyclonal Antibody, MaxPab™
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产品信息
H00026256-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CABYR (NP_619585.1, 1 a.a. approximately 379 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5-1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MISSKPRLVV PYGLKTLLEG ISRAVLKTNP SNINQFAAAY FQELTMYRGN TTMDIKDLVK QFHQIKVEKW SEGTTPQKKL ECLKEPGKTS VESKVPTQME KSTDTDEDNV TRTEYSDKTT QFPSVYAVPG TEQTEAVGGL SSKPATPKTT TPPSSPPPTA VSPEFAYVPA DPAQLAAQML AMATSERGQP PPCSNMWTLY CLTDKNQQGH PSPPPAPGPF PQATLYLPNP KDPQFQQHPP KVTFPTYVMG DTKKTSAPPF ILVGSNVQEA QGWKPLPGHA VVSQSDVLRY VAMQVPIAVP ADEKYQKHTL SPQNANPPSG QDVPRPKSPV FLSVAFPVED VAKKSSGSGD KCAPFGSYGI AGEVTVTTAH KRRKAETEN
靶标信息
Spermatozoa gain fertilization capacitation and hyperactivation after residing in the uterus or oviduct. Calcium, cAMP and protein tyrosine phosphorylation are necessary for the molecular mechanisms that allow for this transformation. CABYR (Calcium-binding tyrosine phosphorylation-regulated protein), also known as Fibrousheathin-2 or Cancer/testis antigen 88, is a 493 amino acid protein that is expressed in sperm flagella and exhibits increased tyrosine phosphorylation during capacitation. There are six named isoforms of CABYR that are produced as a result of alternative slicing events. Specifically, isoform 1 is expressed in the testis, while isoform 3 and isoform 5 are expressed in pancreas, brain and various brain tumors. Isoforms 1, 2 and 6 most likely bind calcium, whereas isoforms 3, 4 and 5 probably do not bind calcium.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: calcium binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2); Calcium-binding protein 86; Calcium-binding tyrosine phosphorylation-regulated protein; calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2); Cancer/testis antigen 88; CT88; fibrousheathin 2; Fibrousheathin II; Fibrousheathin-2; FSP-2; testis tissue sperm-binding protein Li 84P; Testis-specific calcium-binding protein CBP86
基因别名: CABYR; CABYRa; CABYRc; CABYRc/d; CABYRe; CBP86; CT88; FSP-2; FSP2
UniProt ID: (Human) O75952
Entrez Gene ID: (Human) 26256
