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Invitrogen
CACNB2 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-142820
产品规格
种属反应
Human,
Mouse
宿主/亚型
Goat
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Peptide with sequence ECNKQRSRHKSKDRY.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Ammonium sulfate precipitation
保存液
TBS, pH 7.3, with 0.5% BSA
内含物
0.02% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Additional Information: This antibody is expected to recognize all reported isoforms.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:4,000.
靶标信息
The expression of multiple classes of voltage dependent calcium channels (VDCCs) allows neurons to tailor calcium signaling to functionally discrete cellular regions. Although N-Type VDCCs exist before birth which is consistent with a role in migration, most N-Type VDCCs subunit expression is postnatal and is important in the genesis of synaptic transmission in discrete hippocampal fields.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CAB1; CACNLB1; calcium channel voltage-dependent subunit beta 2; calcium channel, voltage-dependent, beta 2 subunit; CCHLB1; lambert-Eaton myasthenic syndrome antigen B; MGC138502; MGC138504; MGC41896; myasthenic (Lambert-Eaton) syndrome antigen B; unnamed protein product
基因别名: CAB2; CACNLB2; CAVB2; Cavbeta2; Cchb2; MYSB
UniProt ID: (Human) Q08289, (Mouse) Q8CC27
Entrez Gene ID: (Human) 783, (Mouse) 12296
voltage-gated calcium channel activity
calcium channel activity
protein binding
high voltage-gated calcium channel activity
actin filament binding
voltage-gated calcium channel activity involved in cardiac muscle cell action potential
voltage-gated calcium channel activity involved in AV node cell action potential
voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels
calcium channel regulator activity
protein kinase binding
protein domain specific binding
identical protein binding
phosphoprotein binding
calcium ion transport
chemical synaptic transmission
neuromuscular junction development
positive regulation of muscle contraction
positive regulation of calcium ion transport
calcium ion import
calcium ion transmembrane transport
protein localization to plasma membrane
membrane depolarization during AV node cell action potential
regulation of heart rate by cardiac conduction
membrane depolarization during atrial cardiac muscle cell action potential
regulation of presynaptic cytosolic calcium ion concentration
positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
visual perception
regulation of voltage-gated calcium channel activity
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Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
