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Abnova
CACNB2 Monoclonal Antibody (6C1)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00000783-M01
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
6C1
抗原
CACNB2 (NP_963890, 213 a.a. approximately 301 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
See Label
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: PSSRKSTPPS SAIDIDATGL DAEENDIPAN HRSPKPSANS VTSPHSKEKR MPFFKKTEHT PPYDVVPSMR PVVLVGPSLK GYEVTDMMQ
靶标信息
The expression of multiple classes of voltage dependent calcium channels (VDCCs) allows neurons to tailor calcium signaling to functionally discrete cellular regions. Although N-Type VDCCs exist before birth which is consistent with a role in migration, most N-Type VDCCs subunit expression is postnatal and is important in the genesis of synaptic transmission in discrete hippocampal fields.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: CAB1; CAB2; CACNB2c; CACNB2e; CACNLB1; calcium channel voltage-dependent subunit beta 2; calcium channel, voltage-dependent, beta 2 subunit; Cavb2i; CCHLB1; ion channel; lambert-Eaton myasthenic syndrome antigen B; MGC138502; MGC138504; MGC41896; myasthenic (Lambert-Eaton) syndrome antigen B; unnamed protein product; voltage-gated calcium channel beta2i subunit
基因别名: CAB2; CACNLB2; CAVB2; Cavbeta2; Cchb2; MYSB
UniProt ID: (Human) Q08289, (Rat) Q8VGC3, (Mouse) Q8CC27
Entrez Gene ID: (Human) 783, (Rat) 116600, (Mouse) 12296
voltage-gated calcium channel activity
calcium channel activity
protein binding
high voltage-gated calcium channel activity
actin filament binding
voltage-gated calcium channel activity involved in cardiac muscle cell action potential
voltage-gated calcium channel activity involved in AV node cell action potential
voltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels
calcium channel regulator activity
protein kinase binding
protein domain specific binding
phosphoprotein binding
identical protein binding
calcium ion transport
chemical synaptic transmission
visual perception
positive regulation of calcium ion transport
calcium ion import
calcium ion transmembrane transport
protein localization to plasma membrane
membrane depolarization during AV node cell action potential
regulation of heart rate by cardiac conduction
membrane depolarization during atrial cardiac muscle cell action potential
regulation of presynaptic cytosolic calcium ion concentration
regulation of voltage-gated calcium channel activity
positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel
neuromuscular junction development
positive regulation of muscle contraction
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