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Abnova
CACNG3 Monoclonal Antibody (3E4)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00010368-M01
产品规格
种属反应
Human,
Rat
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
3E4
抗原
CACNG3 (NP_006530, 199 a.a. approximately 297 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: IYIEKHQQLR AKSHSEFLKK STFARLPPYR YRFRRRSSSR STEPRSRDLS PISKGFHTIP STDISMFTLS RDPSKITMGT LLNSDRDHAF LQFHNSTPK
靶标信息
Calcium Channel gamma-3 is a member of voltage dependent calcium channels (VDCCs) which allows neurons to tailor calcium signaling to functionally discrete cellular regions. Although N-Type VDCCs exist before birth which is consistent with a role in migration, most N-Type VDCCs subunit expression is postnatal, and important in the genesis of synaptic transmission in discrete hippocampal fields. Calcium Channel gamma-3 is a type I transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. Further, Calcium Channel gamma-3 is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family. Calcium Channel gamma-3 gene dysfunction is a susceptibility locus for childhood absence epilepsy.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cacng2; CACNG3; CACNLB3; calcium channel, voltage-dependent, gamma subunit 3; CaVgamma3; neuronal voltage-gated calcium channel gamma-3 subunit; TARP gamma-3; transmembrane AMPAR regulatory protein gamma-3; unnamed protein product; voltage-gated calcium channel gamma subunit
UniProt ID: (Human) O60359, (Rat) Q8VHX0
Entrez Gene ID: (Human) 10368, (Rat) 140724
protein targeting
calcium ion transport
protein localization
transmission of nerve impulse
positive regulation of synaptic transmission, glutamatergic
calcium ion transmembrane transport
postsynaptic neurotransmitter receptor diffusion trapping
neurotransmitter receptor localization to postsynaptic specialization membrane
regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
positive regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
