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Invitrogen
CACNG8 Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-59528
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.2 mg/mL
规格
20 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: DYWLYTRALI CNTTNLTAGG DDGTPHRGGG GASEKKDPGG LTHSGL
Highest antigen sequence identity to the following orthologs: Mouse - 91%, Rat - 91%.
靶标信息
Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: calcium channel, voltage-dependent, gamma subunit 8; CaVGamma8; neuronal voltage-gated calcium channel gamma-8 subunit; TARP gamma-8; transmembrane AMPAR regulatory protein gamma-8
UniProt ID: (Human) Q8WXS5
Entrez Gene ID: (Human) 59283
calcium ion transport
transmission of nerve impulse
positive regulation of synaptic transmission, glutamatergic
calcium ion transmembrane transport
postsynaptic neurotransmitter receptor diffusion trapping
regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
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