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Proteintech
CALCOCO1 Polyclonal Antibody
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产品信息
19843-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CALCOCO1 Fusion Protein Ag13876 (341-691 aa encoded by BC003177)
偶联物
形式
Liquid
浓度
0.13 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: LKEQLRGAQ ELAASSQQKA TLLGEELASA AAARDRTIAE LHRSRLEVAE VNGRLAELGL HLKEEKCQWS KERAGLLQSV EAEKDKILKL SAEILRLEKA VQEERTQNQV FKTELAREKD SSLVQLSESK RELTELRSAL RVLQKEKEQL QEEKQELLEY MRKLEARLEK VADEKWNEDA TTEDEEAAVG LSCPAALTDS EDESPEDMRL PPYGLCERGD PGSSPAGPRE ASPLVVISQP APISPHLSGP AEDSSSDSEA EDEKSVLMAA VQSGGEEANL LLPELGSAFY DMASGFTVGT LSETSTGGPA TPTWKECPIC KERFPAESDK DALEDHMDGH FFFSTQDPFT FE (341-691 aa encoded by BC003177)
靶标信息
CALCOCO1 (calcium-binding and coiled-coil domain-containing protein 1), also known as cocoa, calphoglin, sarcoma antigen NY-SAR-3 or coiled-coil coactivator protein, is a 691 amino acid protein that shuttles between the cytoplasm and nucleus and functions as coactivator for aryl hydrocarbon and nuclear receptors. A member of the CALCOCO family, CALCOCO1 is forms a calphoglin complex with PPA1 and PGM 1 and contains multiple functional domains through which it acts as a component of both the androgen signaling pathway and the Wnt/beta-catenin signaling pathway.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Calcium-binding and coiled-coil domain-containing protein 1; Calphoglin; Coiled-coil coactivator protein; coiled-coil leucine zipper coactivator 1; coiled-coil transcriptional coactivator; granule cell antiserum positive 11; GRIP1-interacting protein; inorganic pyrophosphatase activator; Sarcoma antigen NY-SAR-3
基因别名: 1810009B06Rik; CALCOCO1; calphoglin; CocoA; Gcap11; KIAA1536; mKIAA1536; PP13275; UNQ2436/PRO4996
UniProt ID: (Human) Q9P1Z2, (Rat) Q66HR5, (Mouse) Q8CGU1
Entrez Gene ID: (Human) 57658, (Rat) 246047, (Mouse) 67488
core promoter binding
chromatin binding
transcription cofactor activity
transcription coactivator activity
protein binding
beta-catenin binding
protein C-terminus binding
ligand-dependent nuclear receptor transcription coactivator activity
sequence-specific DNA binding
transcription regulatory region DNA binding
armadillo repeat domain binding
molecular_function
biological_process
Wnt signaling pathway
transcription, DNA-templated
signal transduction
positive regulation of gene expression
intracellular steroid hormone receptor signaling pathway
positive regulation of transcription, DNA-templated
positive regulation of transcription from RNA polymerase II promoter
regulation of nucleic acid-templated transcription
