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Invitrogen
CARP Polyclonal Antibody
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产品信息
PA5-30548
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human CARP. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 1% BSA, 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: 293T, A431, Jurkat, Raji, mouse heart.
Predicted reactivity: Mouse (93%), Rat (95%), Pig (96%), Rabbit (95%), Sheep (97%), Bovine (95%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The protein encoded by this gene is localized to the nucleus of endothelial cells and is induced by IL-1 and TNF-alpha stimulation. Studies in rat cardiomyocytes suggest that this gene functions as a transcription factor. Interactions between this protein and the sarcomeric proteins myopalladin and titin suggest that it may also be involved in the myofibrillar stretch-sensor system.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ankyrin repeat domain 1 (cardiac muscle); Ankyrin repeat domain-containing protein 1; ankyrin-like repeat protein; Cardiac ankyrin repeat protein; cardiac responsive adriamycin protein; Cytokine-inducible gene C-193 protein; Cytokine-inducible nuclear protein; liver ankyrin repeat domain 1
基因别名: ALRP; ANKRD1; bA320F15.2; C-193; C193; CARP; Crap; CVARP; HA1A2; MARP1; MCARP
UniProt ID: (Human) Q15327, (Mouse) Q9CR42
Entrez Gene ID: (Human) 27063, (Mouse) 107765
negative regulation of transcription from RNA polymerase II promoter
regulation of transcription from RNA polymerase II promoter
transcription from RNA polymerase II promoter
positive regulation of neuron projection development
cellular response to drug
skeletal muscle cell differentiation
response to muscle stretch
positive regulation of apoptotic process
positive regulation of DNA damage response, signal transduction by p53 class mediator
positive regulation of transcription from RNA polymerase II promoter
positive regulation of protein secretion
cardiac muscle tissue morphogenesis
cellular response to lipopolysaccharide
cellular response to mechanical stimulus
cellular response to interleukin-1
cellular response to tumor necrosis factor
cellular response to transforming growth factor beta stimulus
negative regulation of nucleic acid-templated transcription
negative regulation of DNA biosynthetic process
muscle cell differentiation
sarcomere organization
cellular response to organic cyclic compound
cellular response to hypoxia
