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Invitrogen
CBWD2 Polyclonal Antibody
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产品信息
PA5-40114
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human CBWD2. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.97 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% Thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: THP-1 cells.
Predicted reactivity: Human (99%), Dog (88%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The CBWD2 gene, a member of the CobW domain-containing (CBWD) gene family, encodes a protein involved in vitamin B12 synthesis. This gene is part of a conserved pathway crucial for cobalamin biosynthesis, typically in microorganisms. In dinoflagellates, the CBWD gene family, including CBWD2, has been identified to play a role in the synthesis and regulation of vitamin B12, essential for various metabolic processes. The CobW domain is implicated in interactions with cobalt, a vital component of the vitamin B12 molecule, suggesting a regulatory or structural role in cobalamin assembly. Research on the CBWD2 gene and its protein products can provide insights into the complex mechanisms of vitamin B12 biosynthesis and its evolutionary significance in eukaryotic organisms, possibly opening avenues for biotechnological applications in vitamin B12 production.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cobalamin synthase W domain-containing protein 2; cobalamin synthetase W domain-containing protein 2; COBW domain-containing protein 2; Zinc-regulated GTPase metalloprotein activator 1B
基因别名: CBWD2; ZNG1B
UniProt ID: (Human) Q8IUF1
Entrez Gene ID: (Human) 150472
