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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Highest antigen sequence identity to the following orthologs: Mouse- 67%, Rat- 67%.
Sequence of this protein is as follows: SIKDKSQQVI VQGVHELYDL EETPVSWKDD TERTNRLVLL GRNLDKDILK QLFIATVTET EKQW
The CBWD2 gene, a member of the CobW domain-containing (CBWD) gene family, encodes a protein involved in vitamin B12 synthesis. This gene is part of a conserved pathway crucial for cobalamin biosynthesis, typically in microorganisms. In dinoflagellates, the CBWD gene family, including CBWD2, has been identified to play a role in the synthesis and regulation of vitamin B12, essential for various metabolic processes. The CobW domain is implicated in interactions with cobalt, a vital component of the vitamin B12 molecule, suggesting a regulatory or structural role in cobalamin assembly. Research on the CBWD2 gene and its protein products can provide insights into the complex mechanisms of vitamin B12 biosynthesis and its evolutionary significance in eukaryotic organisms, possibly opening avenues for biotechnological applications in vitamin B12 production.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cobalamin synthase W domain-containing protein 2; COBW domain-containing protein 2; Zinc-regulated GTPase metalloprotein activator 1B
基因别名: CBWD2; ZNG1B
Entrez Gene ID: (Human) 150472