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Proteintech
CC2D1A Polyclonal Antibody
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
16816-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
已发表种属
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CC2D1A Fusion Protein Ag10355 (1-351 aa encoded by BC064981)
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.4 mg/mL
规格
60 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MHKRKGPPG PPGRGAAAAR QLGLLVDLSP DGLMIPEDGA NDEELEAEFL ALVGGQPPAL EKLKGKGPLP MEAIEKMASL CMRDPDEDEE EGTDEDDLEA DDDLLAELNE VLGEEQKASE TPPPVAQPKP EAPHPGLETT LQERLALYQT AIESARQAGD SAKMRRYDRG LKTLENLLAS IRKGNAIDEA DIPPPVAIGK GPASTPTYSP APTQPAPRIA SAPEPRVTLE GPSATAPASS PGLAKPQMPP GPCSPGPLAQ LQSRQRDYKL AALHAKQQGD TTAAARHFRV AKSFDAVLEA LSRGEPVDLS CLPPPPDQLP PDPPSPPSQP PTPATAPSTT EVPPPPRTLL EA (1-351 aa encoded by BC064981)
靶标信息
This gene encodes a transcriptional repressor that binds to a conserved 14-bp 5'-repressor element and regulates expression of the 5-hydroxytryptamine (serotonin) receptor 1A gene in neuronal cells. The DNA binding and transcriptional repressor activities of the protein are inhibited by calcium. A mutation in this gene results in nonsyndromic mental retardation-3.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: 5-HT1A receptor; Akt kinase-interacting protein 1; five prime repressor element under dual repression-binding protein 1; five repressor element under dual repression-binding protein 1; five' repressor element under dual repression binding protein 1; FLJ20241; FRE under dual repression-binding protein 1; freud-1; lethal (2) giant discs homolog 2; putative NF-kappa-B-activating protein 023N; putative NFkB activating protein; repressor of serotonin-1A receptor; TBK1-associated protein in endolysosomes; unnamed protein product
基因别名: Aki-1; FREUD-1; Freud-1/Aki1; Lgd2; MRT3; RGD1306108; TAPE
UniProt ID: (Human) Q6P1N0, (Mouse) Q8K1A6, (Rat) Q66HA5
Entrez Gene ID: (Human) 54862, (Mouse) 212139, (Rat) 288908
RNA polymerase II core promoter proximal region sequence-specific DNA binding
RNA polymerase II transcription factor activity, sequence-specific DNA binding
transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding
protein binding
cadherin binding
regulation of transcription from RNA polymerase II promoter
positive regulation of I-kappaB kinase/NF-kappaB signaling
negative regulation of snRNA transcription by RNA polymerase II
negative regulation of transcription from RNA polymerase II promoter
regulation of respiratory gaseous exchange by neurological system process
endosome organization
regulation of respiratory gaseous exchange
dendrite arborization
apical dendrite arborization
regulation of postsynapse assembly
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