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Proteintech
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Immunogen sequence: MHKRKGPPGP PGRGAAAARQ LGLLVDLSPD GLMIPEDGAN DEELEAEFLA LVGGQPPALE KLKGKGPLPM EAIEKMASLC MRDPDEDEEE GTDEDDLEAD DDLLAELNEV LGEEQKASET PPPVAQPKPE APHPGLETTL QERLALYQTA IESARQAGDS AKMRRYDRGL KTLENLLASI RKGNAIDEAD IPPPVAIGKG PASTPTYSPA PTQPAPRIAS APEPRVTLEG PSATAPASSP GLAKPQMPPG PCSPGPLAQL QSRQRDYKLA ALHAKQQGDT TAAARHFRVA KSFDAVLEAL SRGEPVDLSC LPPPPDQLPP DPPSPPSQPP TPATAPSTTE VPPPPRTLLE A
This gene encodes a transcriptional repressor that binds to a conserved 14-bp 5'-repressor element and regulates expression of the 5-hydroxytryptamine (serotonin) receptor 1A gene in neuronal cells. The DNA binding and transcriptional repressor activities of the protein are inhibited by calcium. A mutation in this gene results in nonsyndromic mental retardation-3.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 5-HT1A receptor; Akt kinase-interacting protein 1; Coiled-coil and C2 domain-containing protein 1A; Five prime repressor element under dual repression-binding protein 1; five repressor element under dual repression-binding protein 1; five' repressor element under dual repression binding protein 1; FLJ20241; FRE under dual repression-binding protein 1; freud-1; mental retardation, nonsyndromic, autosomal recessive, 3; Putative NF-kappa-B-activating protein 023N; putative NFkB activating protein
基因别名: AKI1; BC016188; CC2D1A; FREUD-1; Freud-1/Aki1; LGD2; MRT3; RGD1306108; Tape
UniProt ID: (Human) Q9H603, (Rat) Q66HA5, (Mouse) Q8K1A6
Entrez Gene ID: (Human) 54862, (Rat) 288908, (Mouse) 212139