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Proteintech
CCAR2 Monoclonal Antibody (2D10F8)
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产品信息
66497-1-IG
产品规格
种属反应
Human,
Pig
宿主/亚型
Mouse
/ IgG2a
分类
Monoclonal
类型
Antibody
克隆号
2D10F8
抗原
CCAR2 Fusion Protein Ag18374 (571-923 aa encoded by BC018269)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: EPEKEEAAK EEATKEEEAI KEEVVKEPKD EAQNEGPATE SEAPLKEDGL LPKPLSSGGE EEEKPRGEAS EDLCEMALDP ELLLLRDDGE EEFAGAKLED SEVRSVASNQ SEMEFSSLQD MPKELDPSAV LPLDCLLAFV FFDANWCGYL HRRDLERILL TLGIRLSAEQ AKQLVSRVVT QNICQYRSLQ YSRQEGLDGG LPEEVLFGNL DLLPPPGKST KPGAAPTEHK ALVSHNGSLI NVGSLLQRAE QQDSGRLYLE NKIHTLELKL EESHNRFSAT EVTNKTLAAE MQELRVRLAE AEETARTAER QKSQLQRLLQ ELRRRLTPLQ LEIQRVVEKA DSWVEKEEPA PSN (571-923 aa encoded by BC018269)
靶标信息
DBC1 is located within a chromosomal region that shows loss of heterozygosity in some bladder cancers. It contains a 5' CpG island that may be a frequent target of hypermethylation, and it may undergo hypermethylation-based silencing in some bladder cancers.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cell cycle and apoptosis regulator protein 2; Cell division cycle and apoptosis regulator protein 2; DBC-1; DBC.1; DBCCR1; DBIRD complex subunit KIAA1967; deleted in breast cancer 1; Deleted in breast cancer gene 1 protein; FAM5A; NET35; p30 DBC; p30 DBC protein
基因别名: CCAR2; DBC-1; DBC1; KIAA1967; NET35; p30 DBC; p30DBC
UniProt ID: (Human) Q8N163
Entrez Gene ID: (Human) 57805, (Pig) 100155718
transcription, DNA-templated
mRNA processing
cellular response to DNA damage stimulus
cell cycle
RNA splicing
response to UV
Wnt signaling pathway
negative regulation of cell growth
regulation of protein stability
negative regulation of proteasomal ubiquitin-dependent protein catabolic process
regulation of DNA-templated transcription, elongation
regulation of circadian rhythm
positive regulation of apoptotic process
negative regulation of catalytic activity
mitochondrial fragmentation involved in apoptotic process
negative regulation of transcription, DNA-templated
rhythmic process
positive regulation of canonical Wnt signaling pathway
regulation of protein deacetylation
regulation of cellular response to heat
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage
positive regulation of DNA damage checkpoint
