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Proteintech
CCDC109B Polyclonal Antibody
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产品信息
20387-1-AP
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CCDC109B Fusion Protein Ag14225 (1-230 aa encoded by BC002633)
偶联物
形式
Liquid
浓度
0.28 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Wet ice (domestic); Dry ice (international)
产品详细信息
Immunogen sequence: MLQRGLWPW RTRLLPTPGT WRPARPWPLP PPPQVLRVKL CGNVKYYQSH HYSTVVPPDE ITVIYRHGLP LVTLTLPSRK ERCQFVVKPM LSTVGSFLQD LQNEDKGIKT AAIFTADGNM ISASTLMDIL LMNDFKLVIN KIAYDVQCPK REKPSNEHTA EMEHMKSLVH RLFTILHLEE SQKKREHHLL EKIDHLKEQL QPLEQVKAGI EAHSEAKTSG LLWAGLALLS I (1-230 aa encoded by BC002633)
靶标信息
Negatively regulates the activity of MCU, the mitochondrial inner membrane calcium uniporter, and thereby modulates calcium uptake into the mitochondrion. Does not form functional calcium channels by itself. Mitochondrial calcium homeostasis plays key roles in cellular physiology and regulates cell bioenergetics, cytoplasmic calcium signals and activation of cell death pathways.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: Calcium uniporter regulatory subunit MCUb, mitochondrial; coiled-coil domain containing 109B; Coiled-coil domain-containing protein 109B; MCUb; mitochondrial calcium uniporter regulatory subunit MCUb
基因别名: CCDC109B; MCUB
UniProt ID: (Human) Q9NWR8
Entrez Gene ID: (Human) 55013
