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Proteintech
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Sequence of this protein is as follows: IELDQVKQQL MHETSRIRAD NKLDINLERS RVTDMFTDQE KQLMETTTEF TKKDTQTKSI ISETSNKIDA EIASLKTLME SNKLETIRYL AASVFTCLAI A
CCDC90B (Coiled-Coil Domain-Containing 90B), also known as MCUR1 (Mitochondrial Calcium Uniporter Regulator 1), is a gene located on chromosome 16p13.3 that encodes a protein involved in mitochondrial function. MCUR1 is a critical component of the mitochondrial calcium uniporter complex, which plays a vital role in regulating mitochondrial calcium uptake. Calcium uptake by mitochondria is essential for cellular metabolism, energy production, and apoptosis. MCUR1 interacts with other components of the uniporter complex to modulate the entry of calcium into the mitochondrial matrix, thereby influencing mitochondrial bioenergetics and reactive oxygen species (ROS) generation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Coiled-coil domain-containing protein 90B, mitochondrial; unnamed protein product
基因别名: 2310015N07Rik; C86558; CCDC90B; CUA003; MDS011; MDS025; RGD1308637
UniProt ID: (Human) Q9GZT6, (Rat) Q4V897, (Mouse) Q8C3X2
Entrez Gene ID: (Human) 60492, (Rat) 308820, (Mouse) 66365