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Invitrogen
CCDC90B Polyclonal Antibody
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产品信息
PA5-52876
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MNSRQAWRLL LSQGRGDRWV SRPRGHFSPA LRREFFTTTT KEGYDRRPVD ITPLEQRKLT FDTHALVQDL ETHGFDKTQA ETIVSALTAL SNVSLDTIYK EMVTQAQQEI TVQQL
Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 75%.
靶标信息
CCDC90B (Coiled-Coil Domain-Containing 90B), also known as MCUR1 (Mitochondrial Calcium Uniporter Regulator 1), is a gene located on chromosome 16p13.3 that encodes a protein involved in mitochondrial function. MCUR1 is a critical component of the mitochondrial calcium uniporter complex, which plays a vital role in regulating mitochondrial calcium uptake. Calcium uptake by mitochondria is essential for cellular metabolism, energy production, and apoptosis. MCUR1 interacts with other components of the uniporter complex to modulate the entry of calcium into the mitochondrial matrix, thereby influencing mitochondrial bioenergetics and reactive oxygen species (ROS) generation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Coiled-coil domain-containing protein 90B, mitochondrial
基因别名: CCDC90B; CUA003; MDS011; MDS025
UniProt ID: (Human) Q9GZT6
Entrez Gene ID: (Human) 60492
