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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA (PubMed:29301961). Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex (PubMed:22952453). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: coiled-coil domain containing 94; coiled-coil domain-containing protein 94; unnamed protein product; YJU2 splicing factor homolog
基因别名: 2900016D05Rik; CCDC94
UniProt ID: (Human) Q9BW85, (Mouse) Q9D6J3
Entrez Gene ID: (Human) 55702, (Mouse) 72886, (Rat) 501285