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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: ITFKTDPENT DYTMEHGATR NFQAEKLLEE EEKRVQKERE DEELNNPMKV LENRTKDSKL EMEVLENLQE LK
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 99%.
Part of the spliceosome which catalyzes two sequential transesterification reactions, first the excision of the non-coding intron from pre-mRNA and then the ligation of the coding exons to form the mature mRNA (PubMed:29301961). Plays a role in stabilizing the structure of the spliceosome catalytic core and docking of the branch helix into the active site, producing 5'-exon and lariat intron-3'-intermediates. May protect cells from TP53-dependent apoptosis upon dsDNA break damage through association with PRP19-CD5L complex (PubMed:22952453). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: coiled-coil domain containing 94; coiled-coil domain-containing protein 94; unnamed protein product; YJU2 splicing factor homolog
基因别名: 2900016D05Rik; CCDC94
UniProt ID: (Human) Q9BW85, (Mouse) Q9D6J3
Entrez Gene ID: (Human) 55702, (Mouse) 72886