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AA Sequence of recombinant protein: FLLPPSTACC TQLYRKPLSD KLLRKVIQVE LQEADGDCHL QAFVLHLAQR SICIHPQNPS LSQWFEHQER KLHGTLPKLN FGMLRKMG.
Preparation: Produced from sera of rabbits immunized with highly pure Recombinant Human CTACK (CCL27). Anti-Human CTACK (CCL27)-specific antibody was purified by affinity chromatography and then biotinylated.
Sandwich ELISA: To detect Human CTACK by sandwich ELISA (using 100 mL/well) a concentration of 0.25-1.0 µg/mL of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech Polyclonal Anti- Human CTACK (500-P294) as a capture antibody, allows the detection of at least 0.2-0.4 ng/well of Recombinant Human CTACK.
Western Blot: To detect Human CTACK by Western Blot analysis this antibody can be used at a concentration of 0.1-0.2 mg/mL. When used in conjunction with compatible development reagents the detection limit for Recombinant Human CTACK is 1.5-3.0 ng/lane, under either reducing or non-reducing conditions.
500-P294BT-1MG will be provided as 2 x 500 µg
CCL27 gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: C-C motif chemokine 27; CC chemokine ILC; chemokine (C-C motif) ligand 27; CTACK; cutaneous T-cell attracting chemokine; Cutaneous T-cell-attracting chemokine; ESkine; IL-11 R-alpha-locus chemokine; IL-11 Ralpha-locus chemokine; Skinkine; small inducible cytokine subfamily A (Cys-Cys), member 27; Small-inducible cytokine A27
基因别名: ALP; CCL27; CTACK; CTAK; ESKINE; ILC; PESKY; SCYA27
UniProt ID: (Human) Q9Y4X3
Entrez Gene ID: (Human) 10850