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Positive control: HCT116 cell lysate, A549 cell lysate, Hela cell lysate, THP-1 cell lysate, SW480 cell lysate, HEK-293 cell lysate, SW480.
Predicted band size: 87 kDa
Subcellular Location: Cytoplasmic granule membrane.
Acts as an assembly platform for Rho protein signaling complexes. Limits guanine nucleotide exchange activity of MCF2L toward RHOA, which results in an inhibition of both its transcriptional activation ability and its transforming activity. Does not inhibit activity of MCF2L toward CDC42, or activity of MCF2 toward either RHOA or CDC42. May be involved in cell cycle regulation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Cell cycle progression protein 1; Cell cycle progression restoration protein 8
基因别名: CCP8; CCPG1; CPR8; KIAA1254
UniProt ID: (Human) Q9ULG6
Entrez Gene ID: (Human) 9236